Delta Debugging
en.wikipedia.org
en.wikipedia.org
http://www.kernel.org/pub/software/scm/git/docs/git-bisect.h...
For all kinds of reductions, mainly code which causes compiler failures.
It is easy to burn a huge amount of CPU time with reductions (large C++ testcases can take a couple of days), it is just important to remember you are saving brain-time, and resist the urge to try to "help" it along.
Is anybody looking at combining delta debugging with Optimizely?