Chernobyl exploded and caught on fire and burned, leading radioactive smoke to spread hundreds of miles. Isn’t this similar to the scenario you propose? We’ve already seen what happens (42 immediate casualties, 1000s of cancer cases). But Europe is still a livable continent, it didn’t turn into the scene of a Fallout video game or whatever.
In comparison, the 2011 Tsunami in Japan killed 15,000, yet people are still allowed to live near the ocean...