I doesn't work for me, but that's probably very application-specific.
I'm not a dev nor a graphic/video artist, my work is motly editing office docs. Why it didn't work for me:
1- OSes are rather bad at handling large monitors. You can't just dumbly Maximize anymore, which is what I always do. Windows positions don't get memorized so your screen is a permanent mess.
2- I need the doc I'm working on, sources, and social/comms/entertainment. That's an ideal setup for 3 monitors and a good stand
3- it's hella expensive.
4- it maps better to how my brain works ?
I want back to 3 medium, cheap monitors, and I'm happier.