The case I find most annoying is driving from one city to another. I don't need directions on how to get to the highway, nor on how to drive straight for 200km[1]. I just want directions when I get close to the city I'm unfamiliar with. Currently, the best solution is turning on directions only when I get a chance to stop near my destination city.
[1] It seems this has gotten better in recent years with less frequent nagging to "proceed straight for 50km" from the app.