My understanding is that the targets of this resent social safety nets. They view them as demeaning, especially since they are capable of work. But the only work traditionally available in the region is coal mining, and that won't be fixed by retraining. So they see the coal, and the ability to work, and grow resentful that they are forbidden from putting these two things together.
They are also attached to the places, and do not wish to leave. Retraining for new jobs in cities, or even different rural areas, means leaving longstanding family homes.
I need to note that I'm not an expert. I'm speaking here thirdhand at best. But I'll note that in the last Presidential election, when asked to choose between a candidate who promised retraining and social safety nets versus one who promised to re-open the coal mines, they overwhelmingly chose the latter.