I don't know if "motivation" per se is studied in this context, but the genetic links for at least "self-regulation"[1], "self-control"[2], and "political ambition"[3] have been studied:

[1]https://psycnet.apa.org/doiLanding?doi=10.1037%2Fpspp0000224

[2]https://www.sciencedirect.com/science/article/pii/S014976341...

[3]https://link.springer.com/article/10.1007/s11109-017-9429-1

A lot of what "motivation" is comes from being able and healthy, and a lot of that certainly comes from genetics, I'd say. If my family's health history didn't prevent me from sleeping more than a few hours a night, I'd certainly be much, much more motivated. No idea how it translates in statistics.

Or as Vincent said in Gattaca: "There is no gene for the human spirit."

As genetics leads to different body types, so does it lead to distinct individual cultures to adapt to genetically defined physiology. So genetics can directly inform culture that way.

The two are inextricably tied. How you think about yourself and your world is based on how you experience it, which is rooted in your genetics and how you were (and weren't) taught to experience it.

We at least learn to motivate ourselves based on how we're taught to do so through the cultures the people around us carry. If some of that is informed by genetics, then it's possible for you to learn to motivate yourself based on someone else's genetics.