Lived on the west-side for a few years in the '10s, so my anecdata may be dated:
The stops are variable in terms of nice-ness. Generally, if there is a shelter (mostly just for lightly falling rain), there is a bum there. Generally, those bums have lived in/about that shelter for a number of years and tend to have mental health problems [0]. Generally, if you an able-bodied male, you should be alright around them during the day. If the stop has no shelter, it's like any other patch of sidewalk.
The Big Blue Busses were mostly ok for commuting. You'd get to work about 10 min later, so with waiting, you spend about another 30 min/day commuting. Most of the time, the busses had sitting space even during commute hours, but not always. You can't count of getting work done on the bus and having a seat the whole way. Also, if your plans have to change in the middle of a Tuesday (your kid gets sick at school, dentist appointment, etc), likely you have to go all the way home to grab your car and then drive to the shindig. That said, I was a LOT calmer than my co-workers that drove in. LA traffic is terrible.
Busses were intermittent and not always on time. So you have to plan for that. Sometimes the piss bus would come along and then you're an hour late, so that sucked.
Generally, if you have to be at work on time, have kids, or are female, taking the bus on the west-side is going to be very very tough to finagle.
[0] The vast majority of homeless people in LA are in vehicles/tents and are trying to stay out of the public view (MANY horrible reasons for this). If you want to help out your fellow homeless citizens, and they NEED the help, here is a good run down: https://la.curbed.com/2018/1/22/16911052/homeless-count-volu...
Please donate time or money, these organizations are saints.