I don't have a handle on the Python implementation landscape, but the various Rubies all regularly contribute to rubyspec[0] and report on how they're doing. And with rvm[1] it's incredibly easy to test code across rubies. From where I'm sitting, it seems dead simple to find the differences and how they could affect me.
0: https://github.com/rubyspec/rubyspec 1: http://rvm.beginrescueend.com/