Big lie or little lie? Did she say she was manager of a large project when she shared most of the management duties with another employee? Or, is she fabricating a medical degree out of thin air?
Everyone puts their best face forward on a resume - and will usually stretching the truth a bit. But most don't engage in outright fraud to land a job. If she is doing that, well she may be facing liability down the road.
It's impossible to discern the severity of the lie from your question alone - for all I know you could be nitpicking douche-bag - OTOH she may be a conniving, money-grubbing harpie. Details, please.