Smoke weed (or do tantric yoga) until you become conscious on a new level (you'll know when you have, if you have difficulties smoke more stronger weed, hash, oil, use a vapourizer or take it orally after extracting it with fat (bake < 300f) or alcohol).

Take mush (of the psilocybin variety) until you understand the nature of the change in consciousness created by the mary jane.

(you can try mescaline anytime after mush if you so wish, it will likely help you either understand the changes or find the connection, but would likely be counterproductive before mush is taken in a significant dose)

Take LSD until you feel an unshakable connection to the universe (start with a massive dose, theres no time like the first, listen to The Beatles [anything after Help! is best] and The Doors for assistance 'breaking on through to the otherside').

Then smoke DMT until you reach 'DMT hyperspace'. (Do not let fire touch the DMT, only touch the flame to the glass [and even then not /right/ under the DMT] take big hits you gotta take 3 big hits and hold them in before you become unable to smoke [mildly difficult]; keep trying.)

At this point you will understand your consciousness in a way science could never teach you, and you won't have to ask us anything about what you should do, you will already know.