My lack of degree was a small barrier to getting some early jobs, part of that was transitioning industries to an industry that can be difficult for junior people to break into (pre-iPhone mobile to games). After my 2nd game industry job at 25 no one cared about my degree.
If your goal is to get a job at FAANG or another big company early in your career you absolutely need a degree. For other jobs it will make things harder but it's not really a requirement. If you still want to work at FAANG 2 or 3 years of industry experience is worth more than a degree.