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According to the Medcram youtube series, NSAIDs in general are known to impair virus replication, but also impair immune function. What is the net result? That is less clear. Many believe that aspirin had a negative effect during the 1918 flu epidemic though.

Video link here: https://www.youtube.com/watch?v=dT6mHi_8V5E

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Apparently aspirin contributed to fatalities via aspirin poisoning, so it did not necessarily have a direct impact on the virus.

Reference: https://en.wikipedia.org/wiki/Spanish_flu#Aspirin_poisoning

According to https://academic.oup.com/cid/article/49/9/1405/301441, the aspirin doses that were used in 1918 (8.0 - 31.2 g/day) were much higher than what people normally take today (usually a max of 3.6g or so).

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