I understand Clinical Depression is more than just feeling down, “depressed”, or demotivated - it’s an actual depression in brain activity (which tends to manifest itself as feelings of sadness, but not necessarily - and people with CD can still laugh, smile, and have a good time... at times).
(I wish they’d change the name of CD to something that avoids the layperson’s concept of “depression” - that alone would help the well-meaning but ignorant people who think it’s just a matter of finding a way to cheer oneself up and certainly nothing to do with serotonin...).