Would you be more comfortable with "we can't estimate the probabilities of all failure modes"? I am sure that all engineers involved in planning the failure-handling systems know that those "calculations of probabilities" are only estimates based on some assumptions.
I think nuclear often gets bad press because you can measure and calculate a lot of risks to a much higher precision than in other industries. Like "x amount of radiation released" where x is actually a very small number but the fact that you can measure it and make an estimate as to how many cancer cases will be caused by it makes it scary, while people don't care much about the risks of, say, coal-mining because thats harder to measure/estimate.