If I am in a conversation with another developer because they asked for my help I will stop talking if it looks like they are 1. either ignoring my advice 2. or have understood enough and are busy doing what they need to do or 3. are busy doing something completely different.

This way I don't waste my time, and I can quickly get back to what I was doing. I tend to spend a lot of time explaining concepts even to people that may know what I am talking about so that I don't have to be interrupted again.

I work better while in an almost empty room with no movement around me and no noises other than the music I am playing.

I tend to spend too much time multitasking so I have disabled all of the notification features on most of the apps I use (such as Mail.app, Adium, Twitter, and others) now they can't interrupt me with an badge stating how many messages I still have unread in my Inbox. It has given me a cleaner experience.

Socially I have started cutting out those people that only demand my time but don't provide me with anything. There is no reason why I should be spending my time writing a long reply when I know you are not going to read it or provide some sort of adequate answer to the questions I posed in an attempt to help you. This is in real life as well, phone calls and the like.