I only run their software in a Windows VM since it installs background services (AAMUpdater, AdobeGCClient) that don't go away even after uninstalling and using their cleanup tool. Not to mention the terrible cloud integration that hangs Chrome after trying to rebuild the font cache out of nowhere.
It's pretty much spyware behavior at this point. Like with certain video games DRM, Adobe software is one of those cases where the pirated version is actually better than the paid one.