I've made it a rule to right click all chrome extensions icons and then set them to "This can read and change data > On www.example.com" on sites I really intend to use them. This prevents them from reading all sites but also prevents the annoyance of reloading the page every-time you need to use the extension. Also some extensions like Likepass inject some really ugly HTML into form fields (it also takes care of that)

It's a pretty useful feature that many people miss.