I mean, to the degree that you need to sort the data at all, it contains informational entropy.
Many "presents as sorted" data structures trade space for time by keeping track of the internal sortedness of chunks of the data, between sortation passes. Heck, any insert-optimized data structure (B+ trees; LevelDB's sorted-string-tables; N-ary tries generally) will get most of its performance gains by being able to guarantee, at node split time, that the children of any particular node are sorted relative to one-another.
So, in many cases, by the very fact that you don't already have metadata attached to your data asserting that it's sorted, it's highly likely to have no branch-predictability.
(Couple that to the fact that load-balancing in OLTP distributed systems favors writes to evenly-keyspace-distributed partitioning keys, ala Dynamo, and you'll frequently find that your inputs to an index-like data structure can be guaranteed random.)