For my usage, I came to conclusion that HTML is the solution. When I need formulas, I may use TeX, for graphs I'll use Excel most of the time. For pictures Gimp etc. HTML is the glue I now use:

- You can reuse it everywhere, publish it on the web, print it

- It's easier to generate

- You can combine it with code much more easily

- Semantic tags in HTML5 (<article>, <section>) remove a big feature gap with LaTeX

- You can reuse your HTML skills for much more other topics.

I use LaTeX quite a bit, still use it for special goals (resumes, articles), but outside the scientific crowd, I don't think it is the best solution any more. I know the typography is better there than on most other software, but on that I rather wished browsers and HTML got better.