Yes and no. Those who play electric guitars with distortion prefer to approach Just Intonation(for a given key) as it doesn't have so much intermodulation.
There is an attempt to tune guitars close to equal temperament trademarked as True Temperament:
https://www.truetemperament.com/faq/
I for one am happy when my 12th and 24th frets are in tune. Solos sound off and weak if these two don't hold.