Tcl seems a bit in a slump nowadays, but I don't think it would need much to get out of it. With a nice interface builder or some "automagic" layout classes the GUIs could be up to par again, although that's probably not even the most important aspect right now. Probably the biggest part missing are packages. TEA isn't that bad, but compared to Eggs/Gems/CPAN it's a bit lackluster. Although this is a bit of a catch-22, I guess.
Hmm, was thinking about what language to use for my next project. Wanted to go with Python, but I think I'll give my old Tcl muscles a good workout again. Had much fun using it in an industrial context, let's see how much hurdles I have to jump for a current web project...