Co-founder at Missive, an email client built entirely in HTML/JS; Electron on desktop; Cordova on mobile.
You can try the app, it's way faster than Mail from Apple. Apple even featured the app multiple times on the mobile App store; again all HTML/JS.
Making fast software in HTML/JS is definitely possible.
An email client is mostly HTML/Style rendering so our use case might be more aligned.
You can learn more about how we made it fast by listening to :
https://syntax.fm/show/184/desktop-and-mobile-apps-with-a-si...