I guess your kind of mentality would be writing everything in assembly. Yes, it is possible to write a website in C or assembly and would probably be more efficient with resources.

No, it doesn't make any sense.

If you calculate you can learn one platform and use the knowledge and toolchain to produce wide variety of projects with less hassle it is difficult to defend using PIC for new projects when the only argument would be that maybe it uses less current in standby mode. The price is that you need to live with with essentially obsolete development environment with no future that you can use only for relatively simple projects.