The paper shows that some of these perceived inefficiencies can be resolved by manual changes on a few lines of code, such as eliminating redundancies. However, the paper then demonstrates that such manual changes can sometimes make the results worse because a particular compiler might not be able to perform inlining or vectorization.
The paper concludes the optimization study by stating, "no compiler is better or worse than another production compiler in all cases." (The study was on GCC, LLVM, and ICC.)