There certainly are pain points. I don't work on this myself, but one of our other engineers wrote this blog post [0] that discusses the experience of running CockroachDB in k8s and why we chose to use it for our hosted cloud product. Another complication mentioned in there is about how to deal with the multi-region case.

[0] https://www.cockroachlabs.com/blog/managed-cockroachdb-on-ku...