In Twitter's case I think you've nailed it. They're so big that effective moderation that pleases everyone is simply unmanageable. What that signals to me is that practically they should be considered a speech platform. Otherwise any attempts to moderate will feel like social cherry-picking. Once classified as a platform we should treat them differently, both legally and colloquially. Legally platforms would be absolved of taking responsibility for the content posted by individuals. And colloquially if people understand they're a platform, and platforms come with self-service tools to make sure unwanted content doesn't show up front and center in your feed, then I think we can collectively mature in our approach towards and response to "dirty" content.
Anyway I don't use twitter either and don't expect nor am I really all that interested in a twitter solution. I'm abstractly defending the social maturity required to tolerate diverging viewpoints without resorting to censoring and banning and extrajudicial mob justice because I believe required to prevent oppressive majority rule.