A Nespresso machine certainly isn't the pinnacle of coffee perfection -- I've just found that it makes a decent and very consistent espresso, lungo or Americano for me. There are times, particularly in the evening, when I just don't want to mess around with grinding and brewing, and I'd much rather have a Nespresso coffee drink than a Keurig one.
That being said, I was under the impression moka pots require a lot of cleanup. For drip, there's a lot of competition, notably the AeroPress, that's only slightly less convenient than the Mr. Coffee machine. But I'm not aware of a product like that for espresso-like drinks.
Moka pots are a little fiddly to clean and, well, a little fiddly in general, I think. I use an Aeropress for brewing most of the time because it's less so. You can make, hmm, "espresso-ish" coffee with it -- it's also actually brewing coffee for a shorter amount of time than usual with greater than usual pressure, when you think about it! -- but I'm generally aiming to get an 8 or 12 ounce cup of normal brewed coffee.
They are typically aluminum so it's not like you have to worry about almost anything growing on/in them