You can’t really defend against a determined adversary. I lived down the road from somebody who had a significant collection of rare coins. He had good locks, hardened doors, and a state of the art security system which was bypassed by using a chainsaw to cut a hole in the wall of his house.
Sounds great until you think about a fire situation. I think we're just going to keep an extra key very close by but that solution only works because we don't have kids; I'm not sure I would go with the double cylinder deadbolt if we did.
(And yes I know it's against the building code but I also know people regularly do double cylinders on their own personal homes. You'd never do it in a rental, AirBnB or commercial building of course.)