American darknet vendor and Costa Rican pharmacist charged
justice.gov
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Having seen opioid addiction up close, I have a hard time not condoning DOJ actions. It’s not perfect, but nothing is.
For chronic cases, I think chronic makes a lot of sense.
Pain helps you get moving. Opioid's don't. Too much pain is debilitating. Surely we can find a formula here (a very very large one).
Cannabis never removes all the pain. I think that's the main feature here.
The cases I've mostly heard about seemed to be that people hot addicted to opioids and the only way to keep it going was to break the law. That eventually got them in trouble. For some drugs it does seem like the government trying to protect you from the drugs do more harm than what the drugs themselves do. Are opioids among them?
As far as I remember, only 10% of people who ever used heroin get addicted to it. But that still leaves 10% at a very high risk, because of their neurochemistry and life circumstances.
So I don't think ALL drugs should be legal.
A recent article which contextualises the work is here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109763/
Obviously it’s lossy to reduce something with this much complexity down to a single dimension but it’s still a helpful tool nonetheless.
How would you know who suffers more on average?
Especially as it is prescribed in the US, where drugs get preferred instead of other interventions. "Back pain? Opioids. No PT, no losing weight, just opioids. No, not even NSAIDS, just go for opioids"
Remember that some drug companies pushed for their medication to be in 12h regimens which increased their dependency potential, as opposed to a shorter interval preferred by doctors?
As a personal experience, opioids don't seem to work much for me on many types of pain.
> people with chronic pain.
Chronic refers to the length of time the pain exists, it doesn't refer to severity.
Here's what the Royal College of Anaesthetists says about opioids
https://fpm.ac.uk/opioids-aware
> Key Messages
> 1. Opioids are very good analgesics for acute pain and for pain at the end of life but there is little evidence that they are helpful for long term pain.
> 2. A small proportion of people may obtain good pain relief with opioids in the long-term if the dose can be kept low and especially if their use is intermittent (however it is difficult to identify these people at the point of opioid initiation).
> 3. The risk of harm increases substantially at doses above an oral morphine equivalent of 120mg/day, but there is no increased benefit: tapering or stopping high dose opioids needs careful planning and collaboration.
> 4. If a patient has pain that remains severe despite opioid treatment it means they are not working and should be stopped, even if no other treatment is available.
> 5. Chronic pain is very complex and if patients have refractory and disabling symptoms, particularly if they are on high opioid doses, a very detailed assessment of the many emotional influences on their pain experience is essential.
He states, "The opposite of addiction is not sobriety, the opposite of addiction is connection." (18:08)
The former U.S. surgeon general, Vivek Murthy, declared loneliness an epidemic, and just wrote a book on it [2].
I believe the biggest challenge we face in the United States centers on emotional health. How do we feel? Whom do we trust? Who do we think loves us? How do we rebuild trust? How do we apologize and forgive? How do we grieve?
I watched a 60 Minutes episode talking about some of the pharma reps trying to convince doctors to prescribe more opioids [3]. One rep, Alec Burlakoff, had this interchange with the interviewer:
> Bill Whitaker: You're preying on these people-- > Alec Burlakoff: Yeah, because they're desperate. They'll try anything. And they may get relief from Subsys initially, But we all know what's gonna happen. We know. We've been doin' this long enough. We know how it ends. > Bill Whitaker: And that is? > Alec Burlakoff: It ends in addiction, withdrawal, pain, suffering, and even death. > Bill Whitaker: And you didn't care about that? > Alec Burlakoff: Back then, I was numb to that.
This reminds me that while I often think that the people who feel disconnected are the ones using the opioids, very often the ones selling them also feel disconnected. How did this man get so numb to selling products that he knew were causing so much pain and suffering to others? How did he get so numb in life in general? More importantly, how do we help him feel more alive?
I agree, I don't think the Department of Justice, especially with a focus on punishment rather than rehabilitation, can lift us out of this hole. I believe it will require a focus on emotional health, on repairing relationships, on helping us feel less distant, more close, to our friends, family, neighbors, and fellow Americans.
[1]: https://www.youtube.com/watch?v=CDpjvFn4wgM [2]: https://www.amazon.com/Together-Connection-Performance-Great... [3]: https://www.cbsnews.com/news/opioid-epidemic-pharmaceutical-...
A man whose professional experience is journalist and has no science, medical, public health, or psychotherapy background... and he’s trying to sell a book.
Is this too harsh a take? Is there a reason I should be taking his opinion seriously?
What is science, if not a never-ending quest to learn more about the universe?
Bold claim, or tortured use of often.
> I wonder how many of our scientific discoveries have come from suggestions (or bold statements) from people in other fields.
A lot of academic fields are fairly siloed from others. One example is presentations at a conference from a subfield that is just slightly oblique from yours is hard to follow because they use different jargon than you. It is getting a little better with some emphasis on interdisciplinary research.
> Sure, many may prove to be false, but I like how you've framed it as a novel opinion that could spur further research into a topic.
From my experience with being blasted by spam ideas just because my contact information is in a university's physics directory, a lot of/most 'novel opinion' is noise.
Fair point, it may not be that often.
> A lot of academic fields are fairly siloed from others. One example is presentations at a conference from a subfield that is just slightly oblique from yours is hard to follow because they use different jargon than you. It is getting a little better with some emphasis on interdisciplinary research.
True, jargon and other aspects can draw divisions really fast. I left the electrical and computer engineering department at my university to pursue international studies because it was interdisciplinary and I could basically build my own major from economics, intl business, anthropology, political science, and other areas. So I'm probably biased towards interdisciplinary stuff and maybe see more of it than there may be.
> From my experience with being blasted by spam ideas just because my contact information is in a university's physics directory, a lot of/most 'novel opinion' is noise.
I can only imagine how many novel theories of the universe you receive and how few have relevance. I still think sometimes we can see patterns in the odd/wrong suggestions they provide and come to hypotheses about things, but maybe more so in some fields than others, and maybe much less directly than I had postulated.
Anyway, really appreciate the back and forth dialogue :-)
I wonder how frequently those opinions come from journalists trying to hawk books on fairly facile premisses tho
What do you mean by it?
I personally don't think that just because he's a journalist without those backgrounds, that he's not capable of learning and presenting truth in those spaces—I see a lot of value in journalistic skills of investigation and interdisciplinary exploration. That being said, it doesn't necessarily mean he's right or that he's not exaggerating or oversimplifying.
I found the podcast episode to be quite compelling to get me more interested in looking up other sources to see whether they agree with him, or if they differ, and in which ways. Even you posting this, questioning his credibility, inspired me to search a bit of what people with more experience in directly related scientific fields have said. Some have questioned whether the studies done with rats extrapolate to humans, some have questioned his seeming disapproval of antidepressants, and more.
I guess it just depends on who and what you trust to give you the truth about this issue. I found the interview illuminating, but that doesn't mean you would or should.
[1] https://en.wikipedia.org/wiki/Johann_Hari#Plagiarism
[2] https://www.theguardian.com/science/brain-flapping/2018/jan/...
On the second point, I think it would be hard to find a book talking about mental health/healthcare that weren't challenged, but I could be wildly wrong on this. I just get the impression that there are many many takes on mental health, especially coming from a variety of fields—psychology, psychiatry, neuroscience, social work, sociology, criminology, etc.—and that I personally believe we still have a lot to learn in this space.
I agree the opinion is probably too sweeping, as I like to qualify most of my statements and some people, especially authors and politicians, often exaggerate theirs.
> Your comment reminds me of an episode of Joe Rogan with Johann Hari [1], talking about what really causes addiction and the failures of the "war on drugs."
I guess I'm a bit confused at such pushback on Hari, but maybe by putting "really" in my statement, with such confidence in the statement, I invited such a challenge.
If I had to take a guess, his income as the vice president of sales probably helped with that.
I guess I still see it as an issue of how connected he felt to himself and other people. I know plenty of people right now, who, if they were offered his salary to do the same job, would never do it. And others who were probably in a field like that and quit because it was getting too much, or maybe even became whistleblowers.
Makes me also think about how some of us can become workaholics to avoid pain in our lives, or crave lots of money to cover up for fears of not having or being enough.
I guess with sociopathy, even if they are behaviors that are very difficult or impossible for a person to change (something I strongly doubt in most cases), I'm still curious as to what brought a person to that stage.
This reminds me of one of the speeches that has touched my heart the most—"Love Your Enemies" by Martin Luther King, Jr.[1]—where he discusses how he strives to love a person, even if he doesn't like how they behave. I see sociopathy similarly—if the person can't change, I may remove myself as much as I can from their behaviors, but still wish them well. I don't know if it will help them change, but it sure helps me feel better :-)
[1]: https://www.youtube.com/watch?v=522wcqUlS0Y
edit added link
You laden them with paralysing amounts of debt in their late teens, force them into capitalistic servitude for the rest of the life. Make sure they earn only just enough to survive. Make sure they work until they are totally exhausted and you can’t squeeze another dollar of productivity out of them.
Make sure they think the only alternative to this is homelessness/total destitution.
Then don’t give them a legal or ethical option that shows them any future other than the above until they are dead, while their bosses boss gets rich.
Then wonder why they act unethically
Genuinely curious: this doesn't really mesh with my understanding. I think opioids are extremely addictive (more so than tobacco or even cocaine or amphetamine) and as a result it's nearly impossible to be a "casual" user (and therefore I don't ever intend to try any opioids). Is there evidence that opioids can be "moderately" used?
The actual drugs here - I’m talking pure, regulated pharmaceutical versions - are pretty benign physiologically. Constipation is about the worst of it.
The combination products (opioid plus something else) are a bit worse - but in those cases it’s the other thing (usually Tylenol) that’s actually hard on your body, especially the liver.
Although it’s much less common these days due to all the regulation, many doctors kept a up successful practices for decades while self medicating heavily.
What gets people killed are either things sold as other things (e.g. heroin laced with fentanyl, which is much stronger) or propel who quit for a while and then go right back to their old dose and OF because their tolerance is gone.
I wonder about the truth of this. I've done a lot of reading at places like Bluelight (for research and curiosity), and it seems there really are a lot of people who set strict guidelines for their drug use and are able to use opioids periodically without addiction.
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1360-0443....
This paper is a great read on the topic. Some suggest more than 50% of heroin users are casual users.
Addiction has a huge situational component. 20% of US GIs in Vietnam were addicted to heroin. When they returned home 90% of them stopped using heroin overnight, indefinitely [2].
We're doing this all wrong.
[1] https://www.theguardian.com/news/2017/dec/05/portugals-radic...
>Addiction has a huge situational component.
Yes, this is exactly what I'm getting at.
>20% of US GIs in Vietnam were addicted to heroin. When they returned home 90% of them stopped using heroin overnight, indefinitely [2].
This seems to contradict your previous point, no? In Vietnam there was of course zero enforcement, outside of the military (I'm being charitable here for reasons that should be obvious), and they returned home to a country where the drug was illegal.
Edit: very interesting, the negative reaction to this comment. What I said is true, so I can only assume that people who are reacting negatively are doing so because they are projecting a view on me that I do not hold.
We have? Can we get a citation on that?
They also returned to their families and loved ones, trying re-introduce themselves to civil society and many figured out that heroin was not helping (illegal or not)
Everyone gets the point you’re making, you’re just not following it through to something meaningful and instead supposing it implies something it doesn’t.
Fits nicely to me.
(1) We have data from 1971 onward, just shy of 50 years, that shows that the "war on drugs" approach used in most of the world has been an abject and total failure. Drug usage remains pervasive, social harms are clear, and we keep throwing people in jail. No progress is made.
(2) A country was doing terribly on every metric, then they made a bold decision that was the opposite of the failed approach everyone else is using.
(3) The results were spectacular.
(4) Your response is "well that'll never work here." This is an implicit endorsement of the failed status quo, and an explicit rejection of evidence in support of an alternative.
> This seems to contradict your previous point, no?
No, it doesn't. It's not at all related to availability or legality of drugs -- drugs are equally available literally everywhere. Nobody in the US who wants to do heroin has any trouble getting heroin, or any other opioids. Accessibility is not the issue. And nobody addicted to heroin goes "oh, well, it's illegal in America, guess I'll stop."
It's evidence to support that we need to end the abject failure of an approach we've squandered 50 years on, and start a new, public health and community support approach to managing addiction. As evidenced by a place it's been overwhelmingly successful.
We literally can't do worse than what we have now, unless you wanted to make drugs mandatory.
The real warning to heed here is that we allow some countries to arrest citizens of other countries who committed crimes outside of their borders.
I know what extradition is, but the concept of spending your whole life in country A, and having country B decide it's time to arrest you and charge you within their jurisdiction makes me uncomfortable. I think more people will oppose it once global power balances start to shift this century.
A bunch of countries suspended extradition to Hong Kong after all the recent power consolidation by China because while they trusted an independent Hong Kong to have reasonable limits on its judiciary they do not trust China to do the same; after all this is a country that dismisses "rule of law". And in fact the whole protest situation was caused by Hong Kong's Government introducing a poorly worded extradition bill that would've essentially given carte blanche for Chinese extradition. https://www.nytimes.com/2019/06/10/world/asia/hong-kong-extr...
Taiwan and Hong Kong do not have extradition treaties.
The murderer is still free in Hong Kong.
The rational response to "hey the country who originally requested the extradition doesn't want to do it anymore" would be to shelve the bill, but at that point the Government and CCP wanted to save face and dug in their heels. Which makes the whole situation an extremely stupid case study of how not to de-escalate a situation.
With that in mind, someone spends their life in country A and does a bunch of things country A considers illegal and involve country B. This isn't an obvious caveat and isn't discussed much, so I can understand where nothing here would surface it.
Extradition treaties mean that things don't become de facto legal because an international border is involved. Though I understand if some might consider such treaties to be simple abuses of hegemonic imperialism.
> I know what extradition is, but the concept of spending your whole life in country A, and having country B decide it's time to arrest you and charge you within their jurisdiction makes me uncomfortable.
That's not a very accurate description of what was alleged to have gone on here. It's more like someone spending their whole life in country A, while running a smuggling network in country B, and only then having country B decide to arrest you for organizing the smuggling of illegal items into their country.
This indictment wouldn't have happened if these guys had restricted their opioid sales to their country of residence.
What’s worrying about anti-American sentiments is that people are willing to advocate for the worst of atrocities just to satiate their emotional state exasperated by media.
I saw similar opinions in countless other threads. America has become the punching bag, thanks to President Trump.
My concern is that countries will ship people to a country they've never been to for things like drug crimes. The standard for what's wrong is going to change in coming decades, and countries that thought it's normal to extradite people for things like drugs are going to find themselves opposing extradition for things like illegal speech, etc.
And there are various charities that send things like birth control or abortion pills to women who can't legally or safely access them. I think if we saw incidences of people being extradited for mailing birth control, most people would agree it's a huge overstep.
Of course there are always exceptions.
The charges were "conspiring with persons to distribute controlled substances, distribution of controlled substances, conspiring with persons to import controlled substances, conspiring to launder money, and laundering of monetary instruments"
I'm pretty sure money laundering, illegally purchasing narcotics, packaging and shipping same internationally are all crimes even in costa rica?
I'm all for tempering goverment oversight, but c'mon... they were ALLEGED drug dealers, and by world standards at least if they get extradited to the USA they might stand trial -- I can think of a few countries where they would just be summarily executed...
I would rather someone be addicted to pharmaceutical grade opioids than street heroin laced with fentanyl and other junk.
The two addictions are more or less the same. Someone addicted to street heroin can substitute pharmaceutical grade opioids. Someone addicted to pharmaceutical grade opioids can substitute street heroin. This is largely a class discrepancy, as the higher tolerance a person has the more expensive the pharmaceutical grade opioid use is compared to street heroin.
Why’s it expensive? Because of the ridiculous war on drugs.
Except pharmaceutical grade opiods are less likely to be cut with deadly shit like fentanyl.
If someone expects heroin but is then given heroin mixed with another chemical, they can overdose quite easily, especially with fentanyl and carfentanyl
One should note that addicts do commit all sorts of crimes to continue their addiction. There probably needs to be some form of back attribution of said acts to those who leech off of addictions
IMO $277M (the value of the bitcoin) should be confiscated as possible and redirected to help victims of such crimes ...
23,900 bitcoin? That was a big business. No wonder why they were targeted.
It's no longer incumbent on anyone else to explain to you why the drug war is immoral, prejudiced, and stupid. Violence is exploding all over the country and homicide clearance rates are at an all time low. The irony of what these fat, beer-swilling thugs at the "Department of Justice" and DEA are doing will not be lost on history.
Shutting down the conversation locks in the status quo.
Thanks to the 13th Amendment, this is not an exaggeration. Thanks to the war on drugs, hundreds of thousands are slaves that wouldn't be otherwise. Manufacturing your license plates, freezing your Big Macs, and picking up your litter by the side of the highway.
At some point, history has to pick a side.
Once you declare everyone who doesn't agree with you an enemy, they stop listening to you, and you've given up on campaigning. This only makes sense if you've given up on convincing people who aren't already convinced.
If you think the time for convincing is over and dialogue has failed, then you seem to be out of non-violent options. Are you raising an armed militia to raid prisons and free non-violent drug offenders?
If dialogue has been dismissed, and you're not advocating violence, what options are there beyond impotently yelling into the echo chamber?
Edit: also, there's a difference between picking a side and declaring enemies.
Edit 2: The great-grand-sibling by cgriswald put it much more eloquently.
You show no compassion or empathy to those who disagree with you so your compassion towards those suffering due to the war on drugs rings false.
I’m pro-legalization and have been for decades; but I’d prefer to live in a world where we don’t build guillotines and dare each other to use them.
Beautifully put. I regret I have but one upvote to give.
DuckDuckGo can't find other uses of this sentence. Is it original? May I quote you?
Large scale substance abuse is IMO an indication something went very wrong in society.
Even if that were true, it would still be possible that it was true because the same innate features which incline toward addiction work against having a happy fulfilled life in the same external conditions that someone without those features would have a happy, fulfilled life.
In other countries, where the answer to pain isn't "throw strong opioids at every chance" the issue is much less severe.
This is fentanyl, drug that is very rarely prescribed. According to Wikipedia only 4% of fentanyl overdoses result from fentanyl obtained by prescription.
I maintain that it is ludicrous to suggest that we should legalize _all_ drugs. We could, however, and IMO should, replace punishment for addictive drug use with drug rehab and a cool-off period, seeing how this shit is almost inevitably deadly in the longer term and is no good for the addict or those around them, at all.
> According to Wikipedia only 4% of fentanyl overdoses result from fentanyl obtained by prescription.
Then why are they manufacturing the other 96% of fentanyl? This is not produced in backyards labs, these are made in professional labs.
This is mostly manufactured illegally in China, to make money. I thought everyone knew about this by now. The country is flooded with this garbage.
https://www.nytimes.com/2019/12/01/world/asia/china-fentanyl...
So, while few people are prescribed fentanyl the root source of the addiction is the massive over-prescription of opioid medication in the US.
As an example, why would someone in Russia stop processing coins because the US DOJ said so?
Virtual currencies aren't the battleground for the US's war on drugs.
Therefore, the person in Russia in your example would have an interest in not dealing with tainted coins, because they couldn't be sold for the same price anymore.
It would basically split Bitcoin into white (provably legit), grey (unsure) and black (illegal) coins.
Yes, this would probably also destroy Bitcoin, but that's a mechanism by which states could obtain extraterritorial power over what people do with Bitcoin.