> It’s not Big Pharma that’s responsible for most retractions

This is not at all surprising to me. Big Pharma has teams of professional statisticians, writers, copy-editors, fact-checkers, etc. and have much more rigorously enforced standards than most academic research institutions. Their bias comes out more in how they frame the study and in the choice of things they study, but I think in general I would trust Big Pharma to be more accurate in reporting their study results than academic labs.