Things that we do not worry about anymore: Javascript, controllers, CORS, JSON, HTTP status codes, API documentation, 3rd party dependencies.
I say we don't worry about javascript and that is true, but I want to be clear that there is still a tiny amount of javascript involved. We do maintain a single "BlazorExtensions.js" file which covers all js interop needs across the entire solution. This file is currently only 120 lines long. So, while we do have javascript, we absolutely do not lose sleep over it anymore.