In general, epistemology is about the root of human knowledge, and why some statement of knowledge represents a justified belief, but those roots never terminate because as Feynman said the Why question never stops recurring, as we dig deeper. In other words, there is no objective truth or any thing for that matter (no pun intended) apart from what we observe (the idea of "primacy of consciousness over matter" per E. Schrödinger et al, a neurophenomenologist view of reality) which means that our justified beliefs depend on how we observe and what we can and cannot conceive of given our finite mental model.
I don't think epistemic relativism is the way to go about life as it basically puts a barrier to further inquiry and pursuit of a truth that we feel is there, and it's the act of digging that allows us to progress, and not the transient truths we derive along the way, as we dig deeper. It's almost as if the truth is a magnet with infinite power and infinite distance that keeps our consciousness in motion or that it sits behind the barrier between being and not being, life and death, etc.
In the wise words of Manuel, I know nothing.
Also, see Bohm's final paper on Hidden Variables and the Implicate Order, the most sane of all metaphysical thoughts that I've come across.