The answer is a qualified "yes". Because not only can it no longer participate in multiple inheritance, but it is very prone to misbehaving silently when used in such a manner, even for experienced Python users.
I say qualified because whether or not the bug warrants fixing is another matter. It's more warranted for public-facing APIs than internal code, since it's less practical for downstream users to modify your code. In your internal code, if your team knows about the issue or just avoids multiple inheritance altogether, or if you have some kind of static analysis to check class hierarchies for you, it might be safe to avoid. (Just listing some considerations that I can think of. There might be more.)
My overall point though was just to illustrate one particular example of a flaw that catches even experienced Python developers off-guard, let alone beginners.