I've been using them for about 10 years now, and they have been extremely reliable, zero-maintenance; and the web-interface is very easy to use and logically organised. (no javascript!)
Their prices aren't too bad either, since domain registration isn't their main priority.
Only downside is that they don't support all domain types, only the legacy GTLDs and a small list of new ones: https://www.nearlyfreespeech.net/services/domains