Beyond that, perception tends to be affected by one's age. When I was young (e.g., in my 20s), all the possibilities of the world seemed open to me and it was just going to be a question of what I would do first - I put everything else into the category "I'll get to that when I have time." I had done a lot to develop my talents and knowledge base, and in a range of areas to boot. But my reading of the "great works" trailed off following college. Time was too limited to get to most of them. But, some day, yes, I would do so. I had never learned to play an instrument. But, when I had time, I would learn piano. I had limited time to do non-business travel, but some day I would make it up.
Of course, "some day" one day comes and you quickly realize that many unrealized hopes and dreams would never in fact be realized. And that includes becoming cultivated in a range of areas. When this fact first strikes you, it truly is depressing. For me, it was the first time in my life that I started to feel "old" (feeling old is not so much chronological as it is a state of mind). You become overwhelmed with the fact that you will never keep up with all the new trends and you will never have the time to fill all the holes in your knowledge base or to do all the things you dreamed of doing.
In time, though, I came to make peace with this sense of restlessness. Life is too short to do everything but life is more than ample enough to do important things, things that count beyond the mundane routines of daily existence. This life is but a breath or, as my 100-year-old grandmother said shortly before she passed on, everything that she had experienced to that point was "but a blink." When you can get to that stage and say, "no regrets" for a life well-led, you can have peace with your finite capacities and your finite existence in this world. There is much that is beautiful to do in this life. You don't need to do it all. You just need to do it well.