I would expect that for most people the time period where there was overlap between config.sys tinkering, Windows, and BBS was pretty small. And likely even less overlap with the era where "3D Studio was on a CDROM".
And to be honest I have always found these stories of "ohmygod I need one extra K of unfragmented low memory, time to tinker with config.sys again" way overblown. I would just do this selective boot thingie that was introduced with some DOS version and period. By the time memmaker was introduced, I don't remember ever needing to use it at all.