How to remove Red-eye in photoshop: http://graphicssoft.about.com/cs/photoshop/ht/apsredeye.htm
How to remove Red-eye in Picasa http://graphicssoft.about.com/od/picasa/ht/redeye.htm
Both pieces of software can remove redeye. For Picasa the instructions boil down to "Click the Fix Red-eye button" whereas Photoshop involves layers, Gaussian blur, saturation, eye droppers.
Which would you say is more accessible for someone maintaining a photo album? Photoshop has more features, but Picasa is more useful to me (in a certain context, obviously.)