Well...I live in a place where we have (in my back yard, except for Bison) all the megafauna present since the ice age. In order of practical danger (most to least), they rank like this: Moose, Bear, Cougar, Snakes, ... Wolves. People are regularly attacked by Moose and fatalities have occurred in the past few decades. People are eaten by bears every few years and injured by bears annually. Cougars present a real danger but they're pretty wary of humans so attacks are more a theoretical risk we hear about from reports concerning mountain bikers in Los Angeles. I never heard of anyone being attacked by a wolf nor anyone being concerned about being attacked by a wolf. Same for Coyotes and Foxes.
I don't hear people suggesting that Moose be killed on sight.