What about Mirror Life? These wrong-handed molecules would be transparent to all existing life
For example from https://en.wikipedia.org/wiki/Amino_acid
> These are all L-stereoisomers ("left-handed" isomers), although a few D-amino acids ("right-handed") occur in bacterial envelopes, as a neuromodulator (D-serine), and in some antibiotics.
> Although D-isomers are uncommon in live organisms, gramicidin is a polypeptide made up from mixture of D- and L-amino acids. Other compounds containing D-amino acids are tyrocidine and valinomycin.
Some bacteria can produce the D- version of the amino acids, and use them in peptides that are natural antibiotics because other bacteria don't know how to destroy them. (Anyway, some other bacteria can are resistant, because they developed a way to destroy them.)