I mean, look at GraphQL, which essentially makes it trivial to implement "plain" CQRS because there are always explicitly separate operations for mutations and queries, and it's easy to have separate object definitions for these operations (this is in direct contrast to many REST architectures, where your verbs - GET, PUT, POST, DELETE, etc. - are fundamentally operating on the same objects). However, underlying in the actual DB there is just a single representation.
But I think when people talk about CQRS these days they are really talking about the underlying data being different (e.g. a log of write operations vs a repository of queryable objects), and that usually implies something like event sourcing, and with that model you have a ton of complexity involved in keeping the different "sides" in sync, and since many update operations also involve queries (i.e. only do this update if something else is true about another object) you get into transactional difficulties as well.