I've had an OCZ Vertex for a couple of years now (I got it a few months after they came out), and it's been fantastic ever since. I've also got two Intel 60GB SSDs in RAID0 in my laptop, which have worked flawlessly since day 1.

However, I purchased an OCZ Vertex 2 for my parents a few months ago as they were building a new computer. About 2 months went by, then one day -- boom -- computer won't boot anymore. I go over and investigate, and it ultimately turns out there's a bug in the latest (read: shipping) firmware in the Vertex 2 which is tripped by some S3 power state transition (e.g. when the computer goes into hibernate mode) and causes the driver controller itself to stop responding. So, your data is OK, but there's no way to flash the drive or anything because the BIOS won't even recognize the drive anymore.

So, my advice is -- get an SSD (or two, in RAID0, if you can afford it), but make sure to keep any really important files backed up (you should be doing this anyway); also, make sure to update your firmware regularly, since the firmware itself may contain bugs that could wreck your drive.