Not a huge number, but that's all you need to support a small town economy. It's like the plight of the rust belt -- you had small communities that relied on manufacturing job to support the local retail and services jobs. When those manufacturing jobs evaporated due to outsourcing those small towns imploded.
There is a big distinction between rural and towns. Even towns of 1-5k people are surprisingly dense since most were built out before urban sprawl became a trend.
Not all jobs can be done remotely, but for the ones that can, the various impediments seem to be dropping away.
After all, dentists and tailors see clients in their homes, and people who sell t-shirts online often manufacture and ship the goods from their home.