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Comment by sgfyd | Hacker News Reader

> specifically wondering about the chance for an MRNA vaccine triggering or deepening autoimmune disease.

I think the medical guidance has been pretty clear that you should not get the vaccine in this case. There are a lot of people who care more about their own safety than yours who may try to change your mind. Don't listen to them; don't get your medical advice on the internet. Find an expert.

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i have a friend that is quite allergic to aluminum, and zinc on contact. these sort of allergies are about hypersensativity, it sounds like you may have problems with any sort of foriegn challenge to your body. A major component of most vaccines is an adjuvent and that is intended to make your immune system extremely ready to recognize foriegn antigens. this means a very good chance you will have a flare up. you want to have sound medical advice from a doctor regarding your own health characteristics. Bare minimum i would want to see direct supervision and observation after a vaccine.

Allergic reactions to adjuvants is an entirely different matter (than autoimmune reactions) and may actually not apply to these vaccines. This just goes to show, don't get your medical advice from HN.

hypersensativity is an autoimmune disorder, and by the way the use of aluminum salts as adjuvent is being phased out, there is great opportunity to formulate the liposomasal delivery vesicle to mimick a pathogenic cell wall.

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