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So mainly a little more SRAM (320K -> 512K) and faster machine learning workloads?

It's also more encryption functionality, 10 more pins of I/O and retains the USB support from the S2.

I, for one, am glad I no longer have to choose between dual core and USB support.

Also, Bluetooth AND USB support combined is killer.

Which might still make a big difference and avoid switching to another chip.