It can be quite difficult for folks like this (Disclaimer: IR1) to find happiness. Crowds, high-stimulus environments, external expectations can be quite chafing.
It can also be tempting to latch onto external things and people, to try to heal something that can't really be healed; but only mitigated (long story, but I went through that kind of thing, myself). I can understand anger, when they don't "fix" us.
I can also relate to the "sleep it off" thing. It would be sort of like Miranda, in Serenity.
It's a really sad story. There are quite a few people like that.