I made an eink clock / status display a while back. The thing ran on a tiny lithium-ion battery for weeks, which was nifty. But the flash when the screen refreshes every minute is super distracting if it's anywhere in your field of view. That to me was a dealbreaker. (If it helps, the datasheet says that it damages the display to refresh it every minute, and it did indeed die mysteriously after a year or so!)

I think I like normal LCDs for status displays. It is possible to redraw the screen without inverting it and drawing a lot of attention, so it is more "ambient".