First, thanks for replying. Perhaps I was to casual in my initial reply. I think we're in agreement that alcohol is a bad idea. I was assuming I was addressing a 20-40 year old entrepreneur, and my impression of these guys, on the forum and those I've met in person, is that they're generally healthy and interested in staying that way, they go to parties now and again, and once in a blue moon wake up with a nasty headache. My goal was to first address that there are generally long term effects and short term effects, and leave it as exercise to the reader to see that there's not much in the 1-week range.

With regards to your specific concerns:

> DTs vs anesthesia

These were intended as two separate examples. I could have made that more clear. I absolutely agree, anesthesia is a very bad idea for someone in DTs. The larger point being, alcohol is a bad idea.

> A single bender is not going to upregulate liver enzymes

I argue a single bender will upregulate liver enzymes. Not a lot, but a little. A single workout will build muscle and improve your physical fitness. Not a lot, but a little. The larger point no doubt being one you're in favor of: alcohol is a bad idea.

> do not recommend to your heavy drinking patients that they should take ibuprofen

I would not recommend a heavy-drinking patient take ibuprofen. That said, alcoholics in the hospital vomiting blood are classically associated with esophageal varices due to a cirrhotic liver, which bleed spontaneously and then they vomit. They are not coming in for gastric ulcers, which generally require days to weeks of NSAIDs, and are more classically associated with aspirin, which irreversibly acetylates the COX enzymes, whereas ibuprofen binds reversibly. The larger point being, alcohol is a bad idea.

> Coffee before food will make this heartburn worse due to the acidity.

I didn't recommend coffee as an antidote to heartburn. I recommended some water and staying upright. The coffee recommendation was for the next morning. The caffeine will activate cAMP, causing some dilation of cerebral blood vessels, getting more profusion to the noggin, helping overcome the headache. The larger point being, alcohol is a bad idea.

> a single serving of yogurt isn't going to have an appreciable effect on your gut flora

Are you arguing against yogurt?

Let me take the opportunity to suggest that I don't advocate drinking as a solution to problems. Quite the opposite. But keep it coming. Glad you came across my comment. Look forward to seeing you around.