Using a magic mouse is near-instant wrist pain for me. Although I like the idea of gestures on the mouse, it just won't work for me. On the other hand, the logitech MX ergo has been stellar for me for the past year!
Also, on the original Mighty Mouse I used to use, I frequently found however hard I pressed, I couldn't click it - my hand just didn't correctly align with where I was supposed to apply pressure.