I use Excel in my data processing workflow. I'll grab a small subset of the data to play around with in excel to see what it is I actually need out of it. Then, I'll do all of the real processing in python along with matplotlib for any charts I need to produce. Excel could almost entirely handle my use cases but there is usually some bit manipulation I need to do because my data is usually telemetry encoded as ASCII. Also making if-else statement in Excel is exhausting.

I could also just use MATLAB but I'm more used to using python.