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I'm not saying it isn't, but these organisms evolved over millions of years to adapt to these environments, whereas the extreme conditions caused by human activity are happening on a much shorter time scale, probably too short for organisms to be able to adapt.

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It is pretty hard to imagine any particular set of conditions short of total planetary surface destruction that would make all extremophiles go extinct - and as long there is enough of them, they will start spreading again.

Any particular species, including humans that lives on Earth is unlikely to survive catastrophic changes - but life will come back and spread into the newly freed and opened niches, just as it did before multiple times.

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